Le Cran

COMBINATION OF LIVE PROBIOTIC BACTERIA FOR COMPLEX TREATMENT OF URINARY TRACT INFECTIONS.

  • Restores intestinal microflora
  • Possesses additional urinary antiseptic effect
  • Intensifies antiseptic effect of antimicrobic agents

Formulation.

1 capsule contains:

Highly efficient combination of live probiotic bacteria (Bifidobacterium bifidum, Lactobacillus acidophilus, Streptococcus thermophiles) – not less than 1.0×109 CFE/g, cranberry extract – 100 mg, vitamin C – 60 mg.

Necessity of dysbacteriosis prevention

in course of antibiotic therapy.

In course of antimicrobic treatment of infection-inflammatory diseases of urinary tracts (pyelonephritis, cystitis, urethritis, etc.) the eradication of causative agents of above-mentioned diseases is accompanied with inhibition of vital activity of normal intestinal microflora. Development of dysbacteriosis is most probable in case of application of the following antibiotics: Clindamycin and Aminopenicillins (Ampicillin, Amoxicillin, and Amoxicillin with beta-lactamase inhibitors), Macrolides, and Cephalosporins (including parenteral). Patients with dysbacteriosis mainly complain of sensation of discomfort in abdomen, hyper gas-formation, changes of stool (diarrhoea, constipations or unstable stool), and colicky abdominal pains. Due to this, application of drugs containing probiotic bacteria of normal human intestinal microflora is the main possibility to prevent development of dysbacteriosis.

Plant urinary antiseptics in course of combined treatment of

infection-inflammatory diseases of urinary tracts.

Medicinal plants that possess urinary antiseptic effect are often used in course of combined treatment of infection-inflammatory diseases of urinary tracts as an additional component to basic therapy or as a monotherapy – in course of prophylaxis of chronic diseases (first of all, chronic pyelonephritis). Irrespective of a large amount of medicinal plants used with this purpose the most studied and widely-used are extract substances received from ordinary cranberry.

Le CranTM. Pharmacological Properties.

Bacteria contained in Le CranTM maximally quickly inhibit growth and development of pathogenic microflora, possess high antagonist activity against the wide range of pathogenic and opportunistic pathogenic microorganisms, and prevent development of intestinal dysbacteriosis. Le CranTM maximally quickly inhibits growth and development of pathogenic microflora, improves parietal digestion, and increases non-specific resistance of organism.

Cranberries extract (organic acids, anthocyanins, anthocyanidins, flavonoids) contained in Le CranTM possesses antimicrobic action and intensifies effect of antibacterial drugs:

  • Organic acids – acidize urine, and create unfavourable conditions for reproduction of pathogenic microorganisms;
  • Anthocyanins, anthocyanidins, and flavonoids – inhibit adhesion (adherence) of pathogenic bacteria to mucous membranes of urinary tract, prevent infection of mucous membranes of organism, which is the most important for prevention of adhesion and further infection with Escherichia coli.

Method of Application and Dosage.

Adults and children aged 12 and above: take 2 capsules twice a day with or after the meals. Do not open the capsule. Duration of treatment is usually 2 weeks. Repeat treatment if necessary. It is recommended to consult a doctor before application.

In case of pregnant and during breast-feeding the daily dose and duration of treatment are determined individually by the doctor.

Recommendations for Application.

Le CranTM is a source of probiotic bacteria, biologically active substances of plant origin, and vitamin C.

Recommended:

-       for prevention and treatment of dysbacteriosis caused by application of antibiotics in urology and gynaecology;

-       as part of combined treatment of urinary infections and inflammatory processes in gynaecological practice accompanied by dysbacteriosis.

 Contraindications.

Individual sensitivity to any components.

Manufacturer Name, Full Address, and Telephone Number.

OLIGOCAPS DEVELOPPEMENT Ltd., rue Jean Rostand, Zoopôle Saint Brieuc-Ploufragan, 22440 Ploufragan, FRANCE. Tel.: +33 296 766 355.

Le CranTM is the only probiotic registered in Ukraine which possesses additional urinary antiseptic effect.